What does doxorubicin hydrochloride do?

What does doxorubicin hydrochloride do?

Doxorubicin is a type of chemotherapy drug called an anthracycline. It slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2.

When do you take doxorubicin?

Doxorubicin is used to treat different types of cancers that affect the breast, bladder, kidneys, ovaries, thyroid, stomach, lungs, bones, nerve tissues, joints, and soft tissues. Doxorubicin is also used to treat Hodgkin lymphoma, non-Hodgkin lymphoma, and certain types of leukemia.

Does doxorubicin shrink tumors?

Yes, if Adriamycin is effective against cancer cells, it will shrink cancerous tumors.

What cancers does doxorubicin treat?

Doxorubicin hydrochloride is approved to be used alone or with other drugs to treat:

  • Acute lymphoblastic leukemia (ALL).
  • Acute myeloid leukemia (AML).
  • Breast cancer.
  • Gastric (stomach) cancer that is metastatic.
  • Hodgkin lymphoma.
  • Neuroblastoma that is metastatic.
  • Non-Hodgkin lymphoma.
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What cancers are treated with doxorubicin?

What does doxorubicin do to the heart?

Doxorubicin May Cause Heart Damage While other anthracyclines (like epirubicin and mitoxantrone) may also cause heart damage, the chances are more common with doxorubicin. Doxorubicin causes both early and late heart damage (also called cardiotoxicity).

What are side effects of doxorubicin?

Side Effects

  • Cough or hoarseness accompanied by fever or chills.
  • darkening or redness of the skin (if you recently had radiation treatment)
  • fast or irregular heartbeat.
  • fever or chills.
  • joint pain.
  • lower back or side pain accompanied by fever or chills.
  • pain at the injection site.

What are the long term effects of doxorubicin?

One notable example is heart damage following treatment with Adriamycin (doxorubicin). With this drug, a possible long-term side effect is weakening of the heart muscle, resulting in a decreased ability to pump blood through the body (heart failure).

How does doxorubicin work?

How doxorubicin works. Doxorubicin is a type of chemotherapy drug called an anthracycline. It slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2. Cancer cells need this enzyme to divide and grow.

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Why is doxorubicin red?

Doxorubicin is the generic name for the chemotherapy drug Adriamycin (chemocare.com). Doxorubicin is classified as an anthracycline, and it is used to treat breast cancer, bladder cancer, some leukemias, multiple myeloma, ovarian cancer and uterine cancer, among others (chemocare.com). It has the nickname “the red devil” due to its red color.

What is doxorubicin IV?

Doxorubicin is administered via an intravenous (IV) injection through a central line or a peripheral venous line, and the drug is given over several minutes. Doxorubicin can also be given by continuous infusion through a central catheter line. There is no pill form of Doxorubicin. Doxorubicin is a vesicant.