What is first line treatment for dyslipidemia?

First-line agents for dyslipidemia include HMG CoA reductase inhibitors (statins), which target LDL cholesterol, and fibric acid derivatives (fibrates), which target triglycerides. Second-line agents include bile acid sequestrants and nicotinic acid (niacin).

How do you classify dyslipidemia?

The three main blood levels collected to assess for dyslipidemia is triglycerides(TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C). High triglyceride levels (>1.7 mmol/L fasting) can indicate dyslipidemia.

What is dyslipidemia treatment?

The most commonly used options for pharmacologic treatment of dyslipidemia include bile acid–binding resins, HMG-CoA reductase inhibitors, nicotinic acid and fibric acid derivatives. Other possibilities in selected cases are estrogen replacement therapy, plasmapheresis and even surgery in severe, refractory cases.

What does a hypolipidemic drug do?

hypolipidemic drug, also called lipid-lowering drug, any agent the reduces the level of lipids and lipoproteins (lipid-protein complexes) in the blood. Lipoproteins bind cholesterol and can accumulate in blood vessels.

Who proposed the classification of dyslipidemia?

What is the Frederickson Classification of dyslipidemias? Author: Henry J Rohrs, III, MD; Chief Editor: Stuart Berger, MD more…

Who Fredrickson classification?

WHO/Fredrickson classification of primary hyperlipidaemias

What is the goal of management of dyslipidemia?

The goal is to reduce LDL concentrations to ≤100 mg/dl [2.60 mmol/l]. The initiation level for behavioral interventions is also an LDL cholesterol of ≥100 mg/dl (2.60 mmol/l). The initial pharmacological therapy should be to use statins.

What is dyslipidemia Medscape?

“Dyslipidemia” refers to an abnormality within the lipid profile, encompassing a variety of disorders relating to elevations in total cholesterol, LDL, or TG, or conversely, lower levels of HDL.

What is an example of hypolipidemic drug?

Statins are hypolipidemic drugs that block the enzyme HMG-CoA (5-hydroxy-3-methylglutaryl-coenzyme A) reductase, which is required for the synthesis of cholesterol. Examples of statins include simvastatin, pravastatin, and lovastatin.

What is clofibrate used for?

Clofibrate is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood.

Is dyslipidemia a diagnosis?

Dyslipidemia is diagnosed by measuring serum lipids. Routine measurements (lipid profile) include total cholesterol (TC), TGs, HDL cholesterol, and LDL cholesterol.

Is hypertriglyceridemia the same as dyslipidemia?

When triglycerides are only affected, this may be referred to as hypertriglyceridemia (high triglyceride levels) or hypotriglyceridemia (low triglyceride levels). Conversely, if an individual has both triglyceride and cholesterol levels affected, this is referred to as a “combined” or “mixed” dyslipidemia.

What are effective medication combinations for dyslipidemia?

Probably the most effective combination for mixed dyslipidemia is a statin with niacin. The use of adjunctive omega-3 supplementation also should be considered especially for patients with elevated triglyceride levels.

What is the most common dyslipidemia treatment?

Dyslipidemia treatment largely depends on a patient’s age, overall health, specific symptoms, and the likelihood of progression to heart disease. The most common dyslipidemia treatment, however, is a carefully-regulated regimen of diet and exercise.

Can dyslipidemia be cured?

Depends. If the hyperlipidemia is fairly mild, weight loss, diet and exercise can cure it. If it is severe, particularly if you have a genetic predisposition, then it cannot be cured.

How to diagnose dyslipidemia?

Dyslipidemia is diagnosed by measuring serum lipids. Routine measurements (lipid profile) include total cholesterol (TC), TGs, HDL cholesterol, and LDL cholesterol. Total cholesterol, triglycerides, and HDL cholesterol are measured directly.