Can you take Arimidex and tamoxifen together?

Benefits of Arimidex Based on the results of this trial, giving Arimidex and tamoxifen at the same time isn’t recommended. The ATAC study found that 5 years of Arimidex is better than 5 years of tamoxifen as the first hormonal therapy for postmenopausal women with early-stage, hormone-receptor-positive breast cancer.

Is it better to take tamoxifen in the morning or at night?

Tamoxifen may be taken at any time of the day but should be taken at the same time each day. it is within 12 hours of the missed dose.

Which has worse side effects tamoxifen or anastrozole?

“Tamoxifen significantly increased the severity of vasomotor symptoms, bladder control, and gynecologic symptoms compared with anastrozole, while anastrozole-treated patients had significantly increased severity of musculoskeletal and vaginal symptoms compared to tamoxifen.

When should I switch from Arimidex to tamoxifen?

Conclusions: Switching to anastrozole after the first 2-3 years of treatment was confirmed to improve event-free and relapse-free survival of postmenopausal, node-positive, ER-positive early breast cancer patients already receiving adjuvant tamoxifen.

What drugs should not be taken with anastrozole?

What Other Drugs Interact with Anastrozole?

• bazedoxifene/conjugated estrogens.
• conjugated estrogens.
• estradiol.
• estrogens conjugated synthetic.
• estrogens esterified.
• estropipate.
• ethinylestradiol.
• tamoxifen.

When is the best time to take Arimidex?

Anastrozole is taken as a tablet once a day, with or without food. It’s best to take it at the same time every day. If you miss a dose, you don’t need to take an extra dose the next day. The level of drug in your body will remain high enough from the day before.

Does tamoxifen affect sleep?

Background: Insomnia is a frequent adverse effect reported by women taking tamoxifen, an estradiol receptor-antagonist, for breast cancer.

Which is safer tamoxifen or anastrozole?

The research team concluded that anastrozole is better than tamoxifen at stopping early stage breast cancer coming back after surgery. And that it caused fewer serious side effects.

What’s better Arimidex or tamoxifen?

The ATAC study also indicated that Arimidex is better tolerated than tamoxifen. Both drugs cause hot flashes, but unlike tamoxifen, Arimidex does not cause blood clots or increase the risk of uterine cancer. However, there is a down side to being on Arimidex.

Is Arimidex more effective than tamoxifen?

Earlier ATAC results found that Arimidex was more effective than tamoxifen in reducing the risk of recurrence of early-stage, hormone-receptor-positive breast cancer in postmenopausal women. Other studies comparing tamoxifen to the other two aromatase inhibitors (Aromasin and Femara) have shown similar results.

Do side effects of anastrozole get worse over time?

Side effects that tend to come on quickly include hot flashes, nausea, vomiting, headache, and pain. Many of these will improve after a few days or weeks. Side effects that take longer to come on include high blood pressure, high cholesterol, osteoporosis, and lymphedema.