How much rapamycin should I take for longevity?

The first report, published in 2009, demonstrated that UMHET3 mice fed a diet containing encapsulated rapamycin at 14 ppm (∼2.24 mg/kg/day) beginning at 600 days of age is sufficient to increase lifespan in both male and female animals (Harrison et al., 2009).

Should you take rapamycin?

First, rapamycin and everolimus are FDA-approved drugs, safe for human use. Since 1999, rapamycin has been used by millions of patients with no unexpected problems. One may suggest that rapamycin/everolimus are safe enough for very sick patients, not for healthy people.

Does rapamycin slow aging process?

It has been calculated that rapamycin slows geroconversion by approximately 3-fold [6]. By doing so, rapamycin slows development and aging, reproduction and menopause, and hyperfunction and functional decline [8].

What are the benefits of rapamycin?

Rapamycin (Sirolimus) slows aging, extends life span, and prevents age-related diseases, including diabetic complications such as retinopathy. Puzzlingly, rapamycin can induce insulin sensitivity, but may also induce insulin resistance or glucose intolerance without insulin resistance.

Can I get a prescription for rapamycin?

Green is among a small but growing number of doctors who prescribe drugs “off-label” for their possible anti-aging effects. Metformin is typically prescribed for diabetes, and rapamycin prevents organ rejection after a transplant, but doctors can prescribe drugs off-label for other purposes — in this case, for “aging.”

Why does Peter Attia take rapamycin?

Rapamycin Specifically, rapamycin is typically prescribed by doctors to turn off the immune system during organ transplants. For this a much larger dose or rapamycin is given than the one for lifespan extension.

Does rapamycin cause weight gain?

Currently, rapamycin is a Food and Drug Administration- approved drug to prevent organ rejection in transplant patients [8,14]. However, prolonged use of rapamycin in humans is associated with adverse side effects such as: hypertriglyceridaemia, excessive weight gain and insulin resistance [9,66,67].

Is metformin a rapamycin?

Metformin is typically prescribed for diabetes, and rapamycin prevents organ rejection after a transplant, but doctors can prescribe drugs off-label for other purposes — in this case, for “aging.”

Does Peter Attia take a statin?

Peter Attia claims he no longer takes these drugs. Atorvastatin is a statin-drug that blocks cholesterol. Scientific studies show that not all statins are the same with regards to lifespan extension.