What does it mean when a cancer cell is resistant to a certain drug treatment?

Cancer cells will become resistant to drugs by the mechanisms such as the inactivation of the drug, multi-drug resistance, cell death inhibition (apoptosis suppression), altering in the drug metabolism, epigenetic changing, changes in the drug targets, enhances DNA-repair and target gene amplification.

Is metformin a cancer drug?

The FDA has announced that the common diabetes drug metformin may have unacceptably high levels of a cancer-causing drug. NDMA is a cancer-causing contaminant called N-Nitrosodimethylamine. If you currently take metformin, it’s crucial to talk with your doctor about other treatment options.

What cancers are associated with metformin?

We show in a comprehensive systematic review that in observational studies metformin use might be associated with a significant reduction in the risk of several forms of cancers, including colorectal, liver, pancreatic, stomach, and oesophagus cancer.

What are common treatments that are used to kill or neutralize cancer cells in leukemia?

Common treatments used to fight leukemia include:

• Chemotherapy. Chemotherapy is the major form of treatment for leukemia.
• Targeted therapy.
• Radiation therapy.
• Bone marrow transplant.
• Immunotherapy.
• Engineering immune cells to fight leukemia.
• Clinical trials.

What type of cancer is resistant to chemotherapy?

Most advanced cancers, including ovarian cancers, eventually become resistant to therapy.

Can metformin prevent cancer?

For example, there is evidence for metformin preventing the growth of cancer cells in lung, prostate, colon, and genograph. Since 2005, metformin has been reported to reduce the risk of cancer by up to 23\% worldwide.

What is remission in cancer?

Remission means that the signs and symptoms of your cancer are reduced. Remission can be partial or complete. In a complete remission, all signs and symptoms of cancer have disappeared. If you remain in complete remission for 5 years or more, some doctors may say that you are cured.

Is there a patent on metaformin and syrosingopine?

There is even a recent patent on metaformin combined with rauwolfia to kill cancer Why are we not using them, there is no patent on either drug on its own. Syrosingopine is hard to find. But I am tracking it down and when I get some I shall try it.

What is the connection of syrosingopine with alternative cancer treatment?

Intresting connection of Syrosingopine with an alternative cancer treatment: Syrosingopine is derived from Reserpine. (It is known that Syrosingopine (Singoserp) is pharmacologically and therapeutically similar to Reserpine. Therefore, there is a very good chance that Reserpine has similar anticancer effects.)

What are the side effects of metaformin?

Metaformin a easily non expensive drug widely available used for diabetes Both drugs have no side effects when taken in normal dosages and combined they have been scientifically found to kill cancer. Google these drugs, follow it up.

What is the optimum dose of syrosingopine and metformin?

I have been reading the patent on this, trying to determine the optimum dose for my wife. The patent states the weight to weight ratio between syrosingopine and metformin should be in the range of 1/200 to 1/100, with the optimum being 1/130.