What if lipoprotein A is high?

Lipoprotein (a) is a type of LDL (bad) cholesterol. A high level of lipoprotein (a) may mean you are at risk for heart disease.

How common is high lipoprotein A?

Indeed, elevated Lp(a) is the most common genetic dyslipidemia, with nearly 1 in 5 individuals affected in the United States [ie, based on Lp(a) >50 mg/dL or >120 nmol/L].

Does everyone have lipoprotein A?

Lp(a) is common in the general population, but there are racial differences that may explain why some people are at higher risk of heart disease. South Asians have the highest prevalence, with 35 percent of their population having Lp(a) greater than 50 milligrams per deciliter, followed by Africans at 30 percent.

How does lipoprotein a cause heart disease?

Made in your liver and then entering your bloodstream, lipoprotein(a) has been shown to build up under the inner lining of arteries. This buildup may contribute to the development of atherosclerosis—the formation of fatty plaques in your arteries that can lead to heart disease, heart attack, and stroke.

Is lipoprotein a hereditary?

Early family studies established the genetic nature of the trait and twin studies found that the heritability of Lp(a) is very high, exceeding 90 \% in populations of European and African descent [22, 23].

How can I lower my lipoprotein levels naturally?

A few changes in your diet can reduce cholesterol and improve your heart health:

1. Reduce saturated fats. Saturated fats, found primarily in red meat and full-fat dairy products, raise your total cholesterol.
2. Eliminate trans fats.
3. Eat foods rich in omega-3 fatty acids.
4. Increase soluble fiber.
5. Add whey protein.

Can you live a long life with high lipoprotein A?

We also provide evidence that genetically determined, as well as absolute Lp(a) levels, are associated with the long-term risk of all-cause and cardiovascular mortality in 18 720 participants of the EPIC-Norfolk prospective population study followed up for a mean of 20 years, in which the mortality risk for those with …

Is high lipoprotein treatable?

Lipoprotein apheresis is currently the only therapy approved by the Food and Drug Administration (FDA) for lowering Lp(a) in the United States. Lipoprotein apheresis is a procedure, usually done every two weeks, to remove lipids, including LDL and Lp(a) from the blood.

How do you reduce high lipoprotein A?

To achieve Lp(a) reduction, one evidence-based approach is to initiate therapy with low-dose aspirin and extended-release niacin, titrated from 0.5 g up to 2 g over several weeks.

Which lipoprotein is most associated with a high risk of heart disease?

LDL (low-density lipoprotein), sometimes called “bad” cholesterol, makes up most of your body’s cholesterol. High levels of LDL cholesterol raise your risk for heart disease and stroke.

Can vitamin C lower lipoprotein A?

Vitamin C supplementation lowers serum low-density lipoprotein cholesterol and triglycerides: a meta-analysis of 13 randomized controlled trials.

Can diet lower lipoprotein A?

Background: Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein and is minimally effected by lifestyle changes. While some drugs can reduce Lp(a), diet has not consistently shown definitive reduction of this biomarker.

Do elevated lipoprotein(A) levels increase heart attack risk?

“These findings are consistent with a causal association of elevated lipoprotein (a) levels with increased (heart attack) risk,” study co-author Borge Nordestgaard, MD, and colleagues write. Nordestgaard tells WebMD that the findings justify a large, randomized intervention trial designed to target lipoprotein (a).

What does it mean if my lipoprotein(a) is high?

That means your other risk factors can be normal, but if Lp (a) is high, your risk for heart disease will be higher than if Lp (a) wasn’t high. In this episode, we cover: 4:43 What is lipoprotein (a)?

What is the relationship between LP(A) Levels and heart disease risk?

A 2012 study in people with diabetes found that higher Lp (a) levels did not correlate with an increased risk of heart disease – above the already increased risk from having diabetes. [ ref] A study on women found that Lp (a) levels were only important in cardiovascular disease if the women also had high cholesterol (>220 mg/dl). [ ref]

Is your LP(A) level too high?

You could be doing everything right, frustratingly, and still have a relatively high Lp (a) level. The thing to understand is that Lp (a), in studies, has been associated with high risk of cardiovascular disease and heart attack, and it’s been validated as an independent risk factor for heart disease.