What is benzofuran used for?

Benzofurans are a type of psychoactive drug that are part of the amphetamine and phenylethylamine classes. They are known to produce feelings of euphoria and to stimulate the sympathetic nervous system, or the body’s system that is responsible for the instincts of flight or fight.

Is benzofuran aromatic one?

Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.

Is benzofuran soluble in water?

Air & Water Reactions Highly flammable. May be sensitive to prolonged exposure to air. Very slightly water soluble.

How do you make benzofuran?

Benzofurans can be prepared by various methods in the laboratory. Notable examples include: O-alkylation of salicylaldehyde with chloroacetic acid followed by dehydration (cyclication) of the resulting ether and decarboxylation.

What is coumarin used for?

Warfarin – a coumarin – with brand name, Coumadin, is a prescription drug used as an anticoagulant to inhibit formation of blood clots, and so is a therapy for deep vein thrombosis and pulmonary embolism.

Why is benzofuran a heterocyclic compound?

Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings. Benzofuran is the “parent” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants.

What is pyran ring?

In chemistry, pyran, or oxine, is a six-membered heterocyclic, non-aromatic ring, consisting of five carbon atoms and one oxygen atom and containing two double bonds. The term pyran is also often applied to the saturated ring analog, which is more properly referred to as tetrahydropyran (oxane).

What is the use of quinoline?

Quinoline is used principally for the manufacture of nicotinic acid, which prevents pellagra in humans, and other chemicals. Several methods are known for its preparation, and production of synthetic quinoline exceeds that from coal tar.

Which one is the example of benzofuran derivative?

This colourless liquid is a component of coal tar. Benzofuran is the “parent” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants….Benzofuran.

Why is coumarin banned?

The tonka bean’s distinct flavor is thanks to coumarin, a chemical compound that has been banned in the United States since 1954 because it can cause liver problems in high concentrations.

Is coumarin bad for humans?

Despite its sweet flavor and pleasant aroma, coumarin is a chemical that can have serious effects on health when consumed in high amounts. In fact, high doses have been linked to liver damage, impaired cognitive development and even cancer formation in both animal and human studies.

What is the structure of benzofuran?

Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings. This colourless liquid is a component of coal tar. Benzofuran is the “parent” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants.

What is benzofuran made of?

Benzofuran is a constituent of Coix lachryma-jobi (Job’s tears) and Gentiana lutea (yellow gentian) Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings. It is the parent of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants.

What is benzo Fury (6-APB)?

For its purportedly recreational derivative drug, nicknamed “Benzo Fury”, see 6-APB. Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings. This colourless liquid is a component of coal tar. Benzofuran is the “parent” of many related compounds with more complex structures.

Is benzofuran a heterocycle?

Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals [66].

What are the disadvantages of benzofurans?

Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids. Consequently, ring synthesis is often preferred <51JA754 > to electrophilic substitution.