What is meant by antimicrobial susceptibility resistance quizlet?

Susceptibility? Antibiotic resistance – ability of bacteria and other microorganisms to resist the effects of an antibiotic. Antibiotic susceptibility – antimicrobial agents that would be most effective in treating the infection (Kirby-Bauer)

What is meant by antibiotic susceptibility?

Susceptibility is a term used when microbe such as bacteria and fungi are unable to grow in the presence of one or more antimicrobial drugs. Susceptibility testing is performed on bacteria or fungi causing an individual’s infection after they have been recovered in a culture of the specimen.

What does the term susceptibility mean when describing antimicrobial testing?

Antimicrobial susceptibility tests are used to determine which specific antibiotics a particular bacteria or fungus is sensitive to. Most often, this testing complements a Gram stain and culture, the results of which are obtained much sooner.

What does susceptibility report mean?

Intermediate (i): The sensitivity of a bacterial strain to a given antibiotic is said to be intermediate when it is inhibited in vitro by a concentration of this drug that is associated with an uncertain therapeutic effect.

What is susceptibility testing?

Susceptibility tests determine a microbe’s vulnerability to antimicrobial drugs by exposing a standardized concentration of organism to specific concentrations of antimicrobial drugs. Susceptibility testing can be done for bacteria, fungi, and viruses.

What does a low MIC mean?

Minimum inhibitory concentration (MIC) can be determined by culturing microorganisms in liquid media or on plates of solid growth medium. A lower MIC value indicates that less drug is required for inhibiting growth of the organism; therefore, drugs with lower MIC scores are more effective antimicrobial agents.

How is antimicrobial susceptibility testing performed?

The test is performed by applying a bacterial inoculum of approximately 1–2×108CFU/mL to the surface of a large (150 mm diameter) Mueller-Hinton agar plate. Up to 12 commercially-prepared, fixed concentration, paper antibiotic disks are placed on the inoculated agar surface (Figure 3).

What is sensitive intermediate and resistant?

Sensitive implies that the organism is inhibited by the serum concentration of the drug that is achieved using the usual dosage; intermediate implies that the organisms are inhibited only by the maximum recommended dosage; and resistant implies that the organisms are resistant to the usually achievable serum drug …

How do you test for antimicrobial susceptibility?

The Kirby-Bauer agar diffusion method is well documented and is the standardized method for determining antimicrobial susceptibility. White filter paper disks (6 mm in diameter) are impregnated with known amounts of antimicrobial agents. Each disk is coded with the name and concentration of the agent.

Is a higher or lower MIC better?

What is the difference between MIC and breakpoint?

A breakpoint is a chosen concentration (mg/L) of an antibiotic which defines whether a species of bacteria is susceptible or resistant to the antibiotic. If the MIC is greater than this value the bacteria is considered intermediate or resistant to the antibiotic.

What is another name for the antimicrobial susceptibility test?

Antibiotic resistance testing (also known as antimicrobial susceptibility testing): Laboratory testing performed on bacteria to find out if they are resistant to one or more antibiotics.

What is antimicrobial resistance testing?

Antibiotic resistance testing (also known as antimicrobial susceptibility testing): Laboratory testing performed on bacteria to find out if they are resistant to one or more antibiotics. Antimicrobial: A substance, such as an antibiotic, that kills or stops the growth of microbes, including bacteria, fungi, or viruses.

What is an example of antibiotic resistance?

Penicillin and ciprofloxacin are examples of antibiotics. Antibiotic resistance: Antimicrobial resistance of bacteria. Antibiotic resistance testing (also known as antimicrobial susceptibility testing): Laboratory testing performed on bacteria to find out if they are resistant to one or more antibiotics.

What do the results of antimicrobial susceptibility testing mean?

Results of antimicrobial susceptibility testing show if bacteria are susceptible (can be treated with the drug), intermediate (may be treatable with the drug, but may require adjusted dosage), or resistant (cannot be treated with drug). AST is also referred to as antibiotic susceptibility testing when tests are being performed on bacteria.

What is the meaning of antimicrobial?

Antimicrobial: A substance, such as an antibiotic, that kills or stops the growth of microbes, including bacteria, fungi, or viruses. Antimicrobials are grouped according to the microbes they act against (antibiotics, antifungals, and antivirals).