What is starch 1500?

Starch 1500® is a partially pregelatinized maize starch manufactured exclusively for the pharmaceutical industry in dedicated cGMP facilities. The production procedure involves a physical modification of the starch resulting in the combined benefits of both the soluble and insoluble functionality.

What is the difference between starch and pregelatinized starch?

An alternative to native corn starch or polymers for wet granulations is pregelatinized starch. This is a starch that has been previously gelatinized and dried to powder form. Partially pregelatinized starches on the other hand, have a mixture of properties of both native and fully gelatinized starches.

What is a pregelatinized starch?

Definition: Prepared from starch or flour, pregelatinized starch easily dissolves in cold liquids eliminating a heating step in manufacturing and becoming viscous like gelatin. It is widely used in foods and pharmaceuticals and also in several other industries including mining/drilling, construction and textiles.

What is pregelatinized starch made from?

Pregelatinized starch derives primarily from corn, has been cooked and then dried. Instant puddings, pie fillings, soup mixes, salad dressings, candy often contain pregelatinized starch. Pregelatinized starches (dried, cooked starches) are highly digestible.

What is sodium starch glycolate?

Abstract. Sodium starch glycolate is a commonly used super-disintegrant employed to promote rapid disintegration and dissolution of IR solid dosage forms. It is manufactured by chemical modification of starch, i.e., carboxymethylation to enhance hydrophilicity and cross-linking to reduce solubility.

Is starch a dry binder?

Starch As Binder Dry binders used for direct compaction must exhibit cohesive and adhesive forces so that when compacted the particles agglomerate.

What temperature does cornstarch Gelatinize?

Gelatinization temperature of starches from select plants

How do you pronounce pregelatinized?

Starts here1:01How To Say Pregelatinized – YouTubeYouTube

What is glycolate type A?

Sodium starch glycolate type A potato is the sodium salt of carboxymethyl ether of starch from potato origin. Starch glycolates are also of rice, wheat or corn origin. It is a white to off-white, tasteless, odorless, relatively free-flowing powder.

What is Primojel?

PRIMOJEL (SODIUM STARCH GLYCOLATE) is the carboxymethyl ether sodium salt. It is a whit to off white tasteless, odorless powder. It is used in pharmaceutical industry as an excipient helping in rapid disintegration.

Is starch a good disintegrant?

Starch is also one of the most commonly used tablet disintegrants at concentrations of 3–15\% w/w. However, unmodified starch does not compress well and tends to increase tablet friability and capping if used in high concentrations.

What is a starch 1500 excipient?

Starch 1500 is a proven and trusted unique pharmaceutical excipient, manufactured exclusively for the global pharmaceutical industry. Starch 1500 is particularly effective with moisture sensitive actives and low dose applications.

What is the advantage of starch 1500 over povidone?

Starch 1500 performed as improved hardness and friability compared with those pr epared with povidone. The formulation of Lamivudine that utilized a super disintegrant. High shear wet gran ulation is also well suited for the use of partially pregelatinized starches.

What is co-Processed starch excipient used for?

Provides excellent stability for moisture sensitive drugs and cost eu001eective content uniformity as a carrier for low dose APIs. StarCap 1500® co-processed starch excipient is a mix of globally accepted excipients (corn starch and pregelatinized starch) designed for use in capsules and tablets.

Is wet granulation suitable for the use of partially pregelatinized starches?

High shear wet gran ulation is also well suited for the use of partially pregelatinized starches. Keywords: Starch 1500, binder, disintegrant, lamivudine tablets, wet granulation. both binder and disintegran t (Herbert et al., 1989).