Why do some vaccines hurt more than others?

They’re designed to start an immune response, which naturally causes an inflammatory reaction in your body. As that happens, the body makes and delivers antibodies to the injection site. “It’s normal for some vaccines to hurt more than others. Overall, symptoms usually last less than a few days.

Which type of injection is more painful?

Our findings show that the speed of injection does not have any impact on perceived pain, whereas injection of a large volume (2250 µL) and thigh injections are statistically more painful than respectively injections with smaller volumes (800 µL or below) and abdomen injections.

Why do tetanus shots hurt so much?

If you have received a tetanus shot and your arm is sore, you may be experiencing discomfort due to your body’s production of antibodies in response to the viruses in the vaccine. If the pain persists for more than a few days after your shot, you may need to consult with a medical professional.

Why is intradermal injection painful?

This is probably because fluid was initially accommodated by the skin independent of the effects of retraction. However, as the infusion pressure continued to the rise, the tear in skin created by the needle retraction expanded, possibly leading to tissue damage that facilitated fluid flow and also caused pain.

Why is my injection hurting?

Injection site reactions are usually mild when they do occur. However, sometimes they can indicate something more serious, like an infection or allergic reaction. High fever, swelling, drainage from the injection site, severe pain, or a whole-body response are all reasons to see a healthcare provider for an evaluation.

What is the most painful injection site?

Shots given in muscles — like the deltoid in the upper arm where flu shots are usually given — tend to be more painful than ones that aren’t injected into the muscle, Stewart said.

Why does the Covid vaccine hurt more than other vaccines?

In both the Pfizer and Moderna vaccine clinical trials, more participants had symptoms like headache, fever, and body aches after the second dose. The effects tend to be more intense after the second shot because of the way your immune system responds to vaccines.