Table of Contents
Why does glucose produce 32 ATP in cardiac muscle?
Under aerobic conditions, pyruvate can diffuse into mitochondria, where it enters the citric acid cycle and generates reducing equivalents in the form of NADH and FADH2. These reducing equivalents then enter the electron transport chain, leading to the production of 32 ATP per molecule of glucose.
Why is glucose required for the contraction of skeletal muscle?
Long-term muscle use requires the delivery of oxygen and glucose to the muscle fiber to allow aerobic respiration to occur, producing the ATP required for muscle contraction.
Why do cardiac muscle cells need to produce ATP?
Constant heart activity requires a constant supply of energy in the form of ATP. Because the heart is never truly at rest, its cells are continually producing and using ATP to support contraction and relaxation.
How many net ATP molecules are produced in the skeletal muscles for each glucose molecule?
In addition to ATP, the Krebs cycle produces high-energy FADH2 and NADH molecules, which provide electrons to the oxidative phosphorylation process that generates more high-energy ATP molecules. For each molecule of glucose that is processed in glycolysis, a net of 36 ATPs can be created by aerobic respiration.
How is ATP is produced in cardiac muscle?
The myocardium requires significant energy to contract continually over the human lifetime. These energy needs are met through mitochondria, myoglobins, and rich blood supply from the coronary arteries. The mitochondria generate ATP for the contraction of cardiomyocytes.
How does the heart produce ATP?
Under normoxic conditions, more than 95\% of ATP generated in the heart is derived from oxidative phosphorylation in the mitochondria. The remaining 5\% mainly comes from glycolysis and to a lesser extent from the citric acid cycle (Krebs cycle).
What is the role of phosphocreatine in providing energy for muscle contraction?
What is the role of phosphocreatine (PC) in providing energy during muscle contraction? Phosphocreatine provides a phosphate group to make ATP. Phosphocreatine is used up rapidly during contraction to make ATP. As people get older their metabolic rate slows down.
How is ATP regenerated during muscle activity?
More ATP can be produced during each metabolic cycle, making the fiber more resistant to fatigue. Glycolytic fibers primarily create ATP through anaerobic glycolysis, which produces less ATP per cycle. As a result, glycolytic fibers fatigue at a quicker rate.
Why do the heart muscles need glucose and oxygen?
Oxygen and glucose are necessary components for respiration, the process of releasing energy for cells to perform their functions. When the coronary artery gets blocked, for example by a blood clot, the heart cells are less able to aerobically respire due to decreased delivery of oxygen and glucose.
How is ATP produced from glucose?
During cellular respiration, a glucose molecule is gradually broken down into carbon dioxide and water. Along the way, some ATP is produced directly in the reactions that transform glucose. Much more ATP, however, is produced later in a process called oxidative phosphorylation.
How many ATP does glucose produce?
In a eukaryotic cell, the process of cellular respiration can metabolize one molecule of glucose into 30 to 32 ATP.
Do skeletal muscle cells use ATP?
Muscle and nerve cells are big users of ATP. Nerve cells consume large amounts of glucose, which they use for production of ATP by aerobic respiration. ATP is used for two things in muscle cells: active transport of calcium (Ca++) and movement of motor proteins.